A curated list with Github stars and forks stats based on awesome [awesome-python](https://github.com/vinta/awesome-python), inspired by [fucking-awesome-go](https://github.com/hvnsweeting/fucking-awesome-go)
* [:octocat: localshop](https://github.com/mvantellingen/localshop) - :star: 283 :fork_and_knife: 99 - Local PyPI server (custom packages and auto-mirroring of pypi).
* [:octocat: PlatformIO](https://github.com/ivankravets/platformio) - :star: 1317 :fork_and_knife: 195 - A console tool to build code with different development platforms.
* [:octocat: PyBuilder](https://github.com/pybuilder/pybuilder) - :star: 746 :fork_and_knife: 155 - A continuous build tool written in pure Python.
* [:octocat: IPython](https://github.com/ipython/ipython) - :star: 10352 :fork_and_knife: 3046 - A rich toolkit to help you make the most out of using Python interactively.
* [:octocat: ptpython](https://github.com/jonathanslenders/ptpython) - :star: 1645 :fork_and_knife: 66 - Advanced Python REPL built on top of the [python-prompt-toolkit](https://github.com/jonathanslenders/python-prompt-toolkit).
* [:earth_americas: pathlib](https://pathlib.readthedocs.org/en/pep428/) - (Python standard library in Python 3.4+) An cross-platform, object-oriented path library.
* [:octocat: python-magic](https://github.com/ahupp/python-magic) - :star: 722 :fork_and_knife: 113 - A Python interface to the libmagic file type identification library.
* [:octocat: Unipath](https://github.com/mikeorr/Unipath) - :star: 388 :fork_and_knife: 32 - An object-oriented approach to file/directory operations.
* [:octocat: watchdog](https://github.com/gorakhargosh/watchdog) - :star: 2257 :fork_and_knife: 302 - API and shell utilities to monitor file system events.
* [:octocat: arrow](https://github.com/crsmithdev/arrow) - :star: 3371 :fork_and_knife: 290 - Better dates & times for Python.
* [:octocat: Chronyk](https://github.com/KoffeinFlummi/Chronyk) - :star: 230 :fork_and_knife: 8 - A Python 3 library for parsing human-written times and dates.
* [:earth_americas: dateutil](https://pypi.python.org/pypi/python-dateutil) - Extensions to the standard Python [datetime](https://docs.python.org/2/library/datetime.html) module.
* [:octocat: delorean](https://github.com/myusuf3/delorean/) - :star: 1226 :fork_and_knife: 60 - A library for clearing up the inconvenient truths that arise dealing with datetimes.
* [:octocat: moment](https://github.com/zachwill/moment) - :star: 333 :fork_and_knife: 18 - A Python library for dealing with dates/times. Inspired by [Moment.js](http://momentjs.com/).
* [:octocat: PyTime](https://github.com/shnode/PyTime) - :star: 101 :fork_and_knife: 13 - A easy-use Python module which aims to operate date/time/datetime by string.
* [:earth_americas: pytz](https://launchpad.net/pytz) - World timezone definitions, modern and historical. Brings the [tz database](http://en.wikipedia.org/wiki/Tz_database) into Python.
* [:octocat: when.py](https://github.com/dirn/When.py) - :star: 153 :fork_and_knife: 13 - Providing user-friendly functions to help perform common date and time actions.
* [:octocat: ftfy](https://github.com/LuminosoInsight/python-ftfy) - :star: 1550 :fork_and_knife: 54 - Makes Unicode text less broken and more consistent automagically.
* [:octocat: awesome-slugify](https://github.com/dimka665/awesome-slugify) - :star: 306 :fork_and_knife: 17 - A Python slugify library that can preserve unicode.
* [:octocat: python-slugify](https://github.com/un33k/python-slugify) - :star: 298 :fork_and_knife: 35 - A Python slugify library that translates unicode to ASCII.
* [:octocat: unicode-slugify](https://github.com/mozilla/unicode-slugify) - :star: 224 :fork_and_knife: 38 - A slugifier that generates unicode slugs with Django as a dependency.
* [:octocat: python-docx](https://github.com/python-openxml/python-docx) - :star: 633 :fork_and_knife: 247 - Reads, queries and modifies Microsoft Word 2007/2008 docx files.
* [:octocat: unoconv](https://github.com/dagwieers/unoconv) - :star: 810 :fork_and_knife: 232 - Convert between any document format supported by LibreOffice/OpenOffice.
* [:octocat: xlwt](https://github.com/python-excel/xlwt) / [xlrd](https://github.com/python-excel/xlrd) - :star: 557 :fork_and_knife: 193 - Writing and reading data and formatting information from Excel files.
* [:octocat: PDFMiner](https://github.com/euske/pdfminer) - :star: 1754 :fork_and_knife: 477 - A tool for extracting information from PDF documents.
* [:octocat: PyPDF2](https://github.com/mstamy2/PyPDF2) - :star: 1108 :fork_and_knife: 348 - A library capable of splitting, merging and transforming PDF pages.
* [:octocat: Mistune](https://github.com/lepture/mistune) - :star: 755 :fork_and_knife: 75 - Fastest and full featured pure Python parsers of Markdown.
* [:octocat: Python-Markdown](https://github.com/waylan/Python-Markdown) - :star: 950 :fork_and_knife: 268 - A Python implementation of John Gruber’s Markdown.
* [:octocat: pdoc](https://github.com/BurntSushi/pdoc) - :star: 260 :fork_and_knife: 40 - Epydoc replacement to auto generate API documentation for Python libraries.
* [:earth_americas: config](http://www.red-dove.com/config-doc/) - Hierarchical config from the author of [logging](https://docs.python.org/2/library/logging.html).
* [:earth_americas: ConfigObj](http://www.voidspace.org.uk/python/configobj.html) - INI file parser with validation.
* [:earth_americas: ConfigParser](https://docs.python.org/2/library/configparser.html) - (Python standard library) INI file parser.
* [:earth_americas: profig](http://profig.readthedocs.org/) - Config from multiple formats with value conversion.
* [:earth_americas: cement](http://builtoncement.com/) - Providing a light-weight and fully featured foundation to build anything from single file scripts to complex and intricately designed applications.
* [:earth_americas: click](http://click.pocoo.org/) - A package for creating beautiful command line interfaces in a composable way.
* [:earth_americas: cliff](http://docs.openstack.org/developer/cliff/) - A framework for creating command-line programs with multi-level commands.
* [:earth_americas: Clime](http://clime.mosky.tw) – Clime lets you convert any module into a multi-command CLI program without any configuration.
* [:octocat: Gooey](https://github.com/chriskiehl/Gooey) - :star: 4296 :fork_and_knife: 225 - Turn command line programs into a full GUI application with one line
* [:earth_americas: pyCLI](https://pythonhosted.org/pyCLI/) - Command-line applications supporting standard command line parsing, logging, unit and functional testing.
* [:octocat: bashplotlib](https://github.com/glamp/bashplotlib) - :star: 628 :fork_and_knife: 50 - Making basic plots in the terminal. It's a quick way to visualize data without GUI.
* [:octocat: caniusepython3](https://github.com/brettcannon/caniusepython3) - :star: 251 :fork_and_knife: 31 - Determine what projects are blocking you from porting to Python 3.
* [:octocat: cookiecutter](https://github.com/audreyr/cookiecutter) - :star: 3966 :fork_and_knife: 474 - A command-line utility that creates projects from cookiecutters (project templates). E.g. Python package projects, jQuery plugin projects.
* [:octocat: doitlive](https://github.com/sloria/doitlive) - :star: 747 :fork_and_knife: 22 - A tool for live presentations in the terminal.
* [:octocat: httpie](https://github.com/jakubroztocil/httpie) - :star: 26575 :fork_and_knife: 1694 - A command line HTTP client, a user-friendly cURL replacement.
* [:octocat: PathPicker](https://github.com/facebook/PathPicker) - :star: 3049 :fork_and_knife: 184 - Select files out of bash output.
* [:octocat: percol](https://github.com/mooz/percol) - :star: 2165 :fork_and_knife: 98 - Adds flavor of interactive selection to the traditional pipe concept on UNIX.
* [:octocat: coursera](https://github.com/coursera-dl/coursera) - :star: 4513 :fork_and_knife: 1263 - Script for downloading Coursera.org videos and naming them.
* [:octocat: s3cmd](https://github.com/s3tools/s3cmd) - :star: 2015 :fork_and_knife: 614 - A command line tool for managing Amazon S3 and CloudFront.
* [:octocat: s4cmd](https://github.com/bloomreach/s4cmd) - :star: 495 :fork_and_knife: 100 - Super S3 command line tool, good for higher performance.
* [:octocat: subliminal](https://github.com/Diaoul/subliminal) - :star: 1073 :fork_and_knife: 210 - Library and command line tool to search and download subtitles.
* [:octocat: WikiTeam](https://github.com/WikiTeam/wikiteam) - :star: 126 :fork_and_knife: 40 - Tools for downloading and preserving wikis.
* [:octocat: thumbor](https://github.com/thumbor/thumbor) - :star: 4211 :fork_and_knife: 432 - A smart imaging service. It enables on-demand crop, re-sizing and flipping of images.
* [:octocat: wand](https://github.com/dahlia/wand) - :star: 615 :fork_and_knife: 137 - Python bindings for [MagickWand](http://www.imagemagick.org/script/magick-wand.php), C API for ImageMagick.
* [:earth_americas: python-tesseract](https://code.google.com/p/python-tesseract) - A wrapper class for [Google Tesseract OCR](https://code.google.com/p/tesseract-ocr/).
* [:octocat: pydub](https://github.com/jiaaro/pydub) - :star: 1555 :fork_and_knife: 166 - Manipulate audio with a simple and easy high level interface.
* [:octocat: pyechonest](https://github.com/echonest/pyechonest) - :star: 583 :fork_and_knife: 1123 - Python client for the [Echo Nest](http://developer.echonest.com/docs/) API.
* [:octocat: tinytag](https://github.com/devsnd/tinytag) - :star: 204 :fork_and_knife: 27 - A library for reading music meta data of MP3, OGG, FLAC and Wave files.
* [:octocat: django-countries](https://github.com/SmileyChris/django-countries) - :star: 292 :fork_and_knife: 94 - A Django app that provides country choices for use with forms, flag icons static files, and a country field for models.
* [:octocat: dataset](https://github.com/pudo/dataset) - :star: 2505 :fork_and_knife: 143 - Store Python dicts in a database - works with SQLite, MySQL, and PostgreSQL.
* [:octocat: queries](https://github.com/gmr/queries) - :star: 154 :fork_and_knife: 13 - A wrapper of the psycopg2 library for interacting with PostgreSQL.
* [:octocat: hot-redis](https://github.com/stephenmcd/hot-redis) - :star: 198 :fork_and_knife: 15 - Rich Python data types for Redis.
* [:octocat: redisco](https://github.com/kiddouk/redisco) - :star: 327 :fork_and_knife: 61 - A Python Library for Simple Models and Containers Persisted in Redis.
* [:octocat: guava](https://github.com/flatpeach/guava) - :star: 139 :fork_and_knife: 9 - A lightweight and high performance web framework for Python written in C.
* [:earth_americas: TurboGears](http://www.turbogears.org/) - The Web Framework that starts as a microframework and scales up to a full stack solution.
* [:earth_americas: web.py](http://webpy.org/) - A web framework for Python that is as simple as it is powerful.
* [:earth_americas: web2py](http://www.web2py.com) - A full stack web framework and platform focused in the ease of use.
* [:earth_americas: Carteblanche](http://www.github.com/neuman/python-carteblanche/) - Module to align code with thoughts of users and designers. Also magically handles navigation and permissions.
* [:octocat: django-guardian](https://github.com/lukaszb/django-guardian) - :star: 1248 :fork_and_knife: 331 - Implementation of per object permissions for Django 1.2+
* [:octocat: django-rules](https://github.com/dfunckt/django-rules) - :star: 344 :fork_and_knife: 24 - A tiny but powerful app providing object-level permissions to Django, without requiring a database.
* [:earth_americas: django-cms](https://www.django-cms.org/en/) - An Open source enterprise CMS based on the Django.
* [:earth_americas: djedi-cms](http://djedi-cms.org/) - A lightweight but yet powerful Django CMS with plugins, inline editing and performance in mind.
* [:earth_americas: FeinCMS](http://www.feincms.org/) - One of the most advanced Content Management Systems built on Django.
* [:earth_americas: Kotte](http://kotti.pylonsproject.org/) - A high-level, Pythonic web application framework built on Pyramid.
* [:earth_americas: Mezzanine](http://mezzanine.jupo.org/) - A powerful, consistent, and flexible content management platform.
* [:earth_americas: Opps](http://oppsproject.org/) - A Django-based CMS for magazines, newspapers websites and portals with high-traffic.
* [:earth_americas: Plone](http://plone.org/) - A CMS built on top of the open source application server Zope.
* [:earth_americas: Quokka](http://quokkaproject.org/) - Flexible, extensible, small CMS powered by Flask and MongoDB.
* [:earth_americas: Wagtail](http://wagtail.io/) - A Django content management system.
* [:earth_americas: Widgy](http://wid.gy/) - Last CMS framework, based on Django.
* [:octocat: alipay](https://github.com/lxneng/alipay) - :star: 170 :fork_and_knife: 53 - Unofficial Alipay API for Python.
* [:octocat: merchant](https://github.com/agiliq/merchant) - :star: 843 :fork_and_knife: 150 - A Django app to accept payments from various payment processors.
* [:earth_americas: django-rest-framework](http://www.django-rest-framework.org/) - A powerful and flexible toolkit that makes it easy to build Web APIs.
* [:earth_americas: django-tastypie](http://tastypieapi.org/) - Creating delicious APIs for Django apps.
* [:earth_americas: flask-api](http://www.flaskapi.org/) - Browsable Web APIs for Flask.
* [:earth_americas: flask-restful](http://flask-restful.readthedocs.org/) - An extension for Flask that adds support for quickly building REST APIs.
* [:earth_americas: flask-restless](https://flask-restless.readthedocs.org/en/latest/) - Generating RESTful APIs for database models defined with SQLAlchemy.
* [:octocat: flask-api-utils](https://github.com/marselester/flask-api-utils) - :star: 28 :fork_and_knife: 3 - Flask extension that takes care of API representation and authentication.
* [:octocat: eve](https://github.com/nicolaiarocci/eve) - :star: 3534 :fork_and_knife: 474 - REST API framework powered by Flask, MongoDB and good intentions.
* [:octocat: Flask-OAuthlib](https://github.com/lepture/flask-oauthlib) - :star: 799 :fork_and_knife: 232 - OAuth 1.0/a, 2.0 implementation of client and provider for Flask.
* [:octocat: OAuthLib](https://github.com/idan/oauthlib) - :star: 1242 :fork_and_knife: 269 - A generic and thorough implementation of the OAuth request-signing logic.
* [:octocat: python-oauth2](https://github.com/simplegeo/python-oauth2) - :star: 2500 :fork_and_knife: 971 - A fully tested, abstract interface to creating OAuth clients and servers.
* [:octocat: python-social-auth](https://github.com/omab/python-social-auth) - :star: 2507 :fork_and_knife: 1106 - An easy-to-setup social authentication mechanism.
* [:octocat: rauth](https://github.com/litl/rauth) - :star: 1446 :fork_and_knife: 149 - A Python library for OAuth 1.0/a, 2.0, and Ofly.
* [:octocat: sanction](https://github.com/demianbrecht/sanction) - :star: 158 :fork_and_knife: 38 - A dead simple OAuth2 client implementation.
* [:earth_americas: elasticsearch-py](http://www.elasticsearch.org/guide/en/elasticsearch/client/python-api/current/) - The official low-level Python client for [Elasticsearch](https://www.elastic.co/products/elasticsearch).
* [:octocat: django-activity-stream](https://github.com/justquick/django-activity-stream) - :star: 1093 :fork_and_knife: 327 - Generate generic activity streams from the actions on your site.
* [:octocat: Feedly](https://github.com/tschellenbach/Feedly) - :star: 2489 :fork_and_knife: 307 - A library to build newsfeed and notification systems using Cassandra and Redis.
* [:octocat: django-compressor](https://github.com/django-compressor/django-compressor) - :star: 1750 :fork_and_knife: 490 - Compresses linked and inline JavaScript or CSS into a single cached file.
* [:octocat: jinja-assets-compressor](https://github.com/jaysonsantos/jinja-assets-compressor) - :star: 55 :fork_and_knife: 9 - A Jinja extension to compile and compress your assets.
* [:earth_americas: Beaker](http://beaker.readthedocs.org/) - A library for caching and sessions for use with web applications and stand-alone Python scripts and applications.
* [:earth_americas: dogpile.cache](http://dogpilecache.readthedocs.org/) - dogpile.cache is next generation replacement for Beaker made by same authors.
* [:earth_americas: HermesCache](https://pypi.python.org/pypi/HermesCache) - Python caching library with tag-based invalidation and dogpile effect prevention.
* [:octocat: django-celery-ses](https://github.com/StreetVoice/django-celery-ses) - :star: 19 :fork_and_knife: 4 - Django email back end with AWS SES and Celery.
* [:octocat: mailjet](https://github.com/WoLpH/mailjet) - :star: 17 :fork_and_knife: 13 - Mailjet API implementation for batch mailing, statistics and more.
* [:octocat: modoboa](https://github.com/tonioo/modoboa) - :star: 609 :fork_and_knife: 91 - A mail hosting and management platform including a modern and simplified Web UI.
* [:octocat: furl](https://github.com/gruns/furl) - :star: 954 :fork_and_knife: 62 - A small Python library that makes manipulating URLs simple.
* [:octocat: purl](https://github.com/codeinthehole/purl) - :star: 169 :fork_and_knife: 21 - A simple, immutable URL class with a clean API for interrogation and manipulation.
* [:octocat: pyshorteners](https://github.com/ellisonleao/pyshorteners) - :star: 137 :fork_and_knife: 20 - A pure Python URL shortening lib.
* [:octocat: short_url](https://github.com/Alir3z4/python-short_url) - :star: 61 :fork_and_knife: 11 - Python implementation for generating Tiny URL and bit.ly-like URLs.
* [:octocat: webargs](https://github.com/sloria/webargs) - :star: 371 :fork_and_knife: 49 - A friendly library for parsing HTTP request arguments, with built-in support for popular web frameworks, including Flask, Django, Bottle, Tornado, and Pyramid.
* [:earth_americas: BeautifulSoup](http://www.crummy.com/software/BeautifulSoup/bs4/doc/) - Providing Pythonic idioms for iterating, searching, and modifying HTML or XML.
* [:earth_americas: bleach](http://bleach.readthedocs.org/) - A whitelist-based HTML sanitization and text linkification library.
* [:earth_americas: cssutils](https://pypi.python.org/pypi/cssutils/) - A CSS library for Python.
* [:octocat: html5lib](https://github.com/html5lib/html5lib-python) - :star: 526 :fork_and_knife: 115 - A standards-compliant library for parsing and serializing HTML documents and fragments.
* [:octocat: MarkupSafe](https://github.com/mitsuhiko/markupsafe) - :star: 138 :fork_and_knife: 47 - Implements a XML/HTML/XHTML Markup safe string for Python.
* [:octocat: pyquery](https://github.com/gawel/pyquery) - :star: 1048 :fork_and_knife: 98 - A jQuery-like library for parsing HTML.
* [:octocat: untangle](https://github.com/stchris/untangle) - :star: 198 :fork_and_knife: 27 - Converts XML documents to Python objects for easy access.
* [:octocat: xhtml2pdf](https://github.com/chrisglass/xhtml2pdf) - :star: 1158 :fork_and_knife: 419 - HTML/CSS to PDF converter.
* [:octocat: xmltodict](https://github.com/martinblech/xmltodict) - :star: 2166 :fork_and_knife: 211 - Working with XML feel like you are working with JSON.
* [:octocat: RoboBrowser](https://github.com/jmcarp/robobrowser) - :star: 2582 :fork_and_knife: 181 - A simple, Pythonic library for browsing the web without a standalone web browser.
* [:octocat: sumy](https://github.com/miso-belica/sumy) - :star: 686 :fork_and_knife: 141 - A module for automatic summarization of text documents and HTML pages.
* [:octocat: textract](https://github.com/deanmalmgren/textract) - :star: 1765 :fork_and_knife: 167 - Extract text from any document, Word, PowerPoint, PDFs, etc.
* [:earth_americas: django-crispy-forms](http://django-crispy-forms.readthedocs.org/) - A Django app which lets you create beautiful forms in a very elegant and DRY way.
* [:earth_americas: Cerberus](http://python-cerberus.org) - A mappings-validator with a variety of rules, normalization-features and simple customization that uses a pythonic schema-definition.
* [:earth_americas: colander](http://docs.pylonsproject.org/projects/colander/) - A system for validating and deserializing data obtained via XML, JSON, an HTML form post or any other equally simple data serialization.
* [:octocat: kmatch](https://github.com/ambitioninc/kmatch) - :star: 40 :fork_and_knife: 10 - A language for matching/validating/filtering Python dictionaries.
* [:octocat: voluptuous](https://github.com/alecthomas/voluptuous) - :star: 685 :fork_and_knife: 105 - A Python data validation library. It is primarily intended for validating data coming into Python as JSON, YAML, etc.
* [:octocat: django-simple-captcha](https://github.com/mbi/django-simple-captcha) - :star: 390 :fork_and_knife: 157 - A simple and highly customizable Django app to add captcha images to any Django form.
* [:octocat: django-xadmin](https://github.com/sshwsfc/django-xadmin) - :star: 1735 :fork_and_knife: 546 - Drop-in replacement of Django admin comes with lots of goodies.
* [:octocat: flask-admin](https://github.com/mrjoes/flask-admin) - :star: 66 :fork_and_knife: 31 - Simple and extensible administrative interface framework for Flask.
* [:octocat: flower](https://github.com/mher/flower) - :star: 1921 :fork_and_knife: 355 - Real-time monitor and web admin for Celery.
* [:octocat: Wooey](https://github.com/wooey/wooey) - :star: 732 :fork_and_knife: 61 - A Django app which creates automatic web UIs for Python scripts.
* [:octocat: WebSocket-for-Python](https://github.com/Lawouach/WebSocket-for-Python) - :star: 725 :fork_and_knife: 184 - WebSocket client and server library for Python 2 and 3 as well as PyPy.
* [:earth_americas: gunicorn](http://pypi.python.org/pypi/gunicorn) - Pre-forked, partly written in C.
* [:earth_americas: uwsgi](https://uwsgi-docs.readthedocs.org/en/latest/) - A project aims at developing a full stack for building hosting services, written in C.
* [:earth_americas: bjoern](http://pypi.python.org/pypi/bjoern) - Asynchronous, very fast and written in C.
* [:earth_americas: fapws3](http://www.fapws.org/) - Asynchronous (network side only), written in C.
* [:earth_americas: meinheld](http://pypi.python.org/pypi/meinheld) - Asynchronous, partly written in C.
* [:earth_americas: Werkzeug](http://werkzeug.pocoo.org/) - A WSGI utility library for Python that powers Flask and can easily be embedded into your own projects.
* [:octocat: SimpleJSONRPCServer](https://github.com/joshmarshall/jsonrpclib/) - :star: 284 :fork_and_knife: 112 - This library is an implementation of the JSON-RPC specification.
* [:octocat: zeroRPC](https://github.com/dotcloud/zerorpc-python) - :star: 1799 :fork_and_knife: 218 - zerorpc is a flexible RPC implementation based on [ZeroMQ](http://zeromq.org/) and [MessagePack](http://msgpack.org/).
* [:earth_americas: Paramiko](http://www.paramiko.org/) - A Python (2.6+, 3.3+) implementation of the SSHv2 protocol, providing both client and server functionality.
* [:earth_americas: Passlib](https://pythonhosted.org/passlib/) - Secure password storage/hashing library, very high level.
* [:earth_americas: PyCrypto](https://www.dlitz.net/software/pycrypto/) - The Python Cryptography Toolkit.
* [:earth_americas: curses](https://docs.python.org/2/library/curses.html#module-curses) - Built-in wrapper for [ncurses](http://www.gnu.org/software/ncurses/) used to create terminal GUI applications.
* [:earth_americas: kivy](http://kivy.org/) - A library for creating NUI applications, running on Windows, Linux, Mac OS X, Android and iOS.
* [:earth_americas: pyglet](http://www.pyglet.org/) - A cross-platform windowing and multimedia library for Python.
* [:earth_americas: PyQt](http://www.riverbankcomputing.co.uk/software/pyqt/intro) - Python bindings for the [Qt](http://qt-project.org/) cross-platform application and UI framework, with support for both Qt v4 and Qt v5 frameworks.
* [:earth_americas: PySide](http://qt-project.org/wiki/pyside) - Python bindings for the [Qt](http://qt-project.org/) cross-platform application and UI framework, supporting the Qt v4 framework.
* [:earth_americas: Tkinter](https://wiki.python.org/moin/TkInter) - Tkinter is Python's de-facto standard GUI package.
* [:earth_americas: urwid](http://urwid.org/) - A library for creating terminal GUI applications with strong support for widgets, events, rich colors, etc.
* [:earth_americas: wxPython](http://wxpython.org/) - A blending of the wxWidgets C++ class library with the Python.
* [:earth_americas: Cocos2d](http://cocos2d.org/) - cocos2d is a framework for building 2D games, demos, and other graphical/interactive applications. It is based on pyglet.
* [:earth_americas: Panda3D](https://www.panda3d.org/) - 3D game engine developed by Disney and maintained by Carnegie Mellon's Entertainment Technology Center. Written in C++, completely wrapped in Python.
* [:earth_americas: Pygame](http://www.pygame.org/news.html) - Pygame is a set of Python modules designed for writing games.
* [:earth_americas: PyOgre](http://www.ogre3d.org/tikiwiki/PyOgre) - Python bindings for the Ogre 3D render engine, can be used for games, simulations, anything 3D.
* [:earth_americas: PyOpenGL](http://pyopengl.sourceforge.net/) - Python ctypes bindings for OpenGL and it's related APIs.
* [:earth_americas: PySDL2](http://pysdl2.readthedocs.org/) - A ctypes based wrapper for the SDL2 library.
* [:earth_americas: PySFML](http://www.python-sfml.org/) - Python bindings for [SFML](http://www.sfml-dev.org/)
* [:earth_americas: RenPy](http://www.renpy.org/) - A Visual Novel engine.
* [:octocat: PyAutoGUI](https://github.com/asweigart/pyautogui) - :star: 633 :fork_and_knife: 94 - PyAutoGUI is a cross-platform GUI automation Python module for human beings.
* [:octocat: pyshould](https://github.com/drslump/pyshould) - :star: 32 :fork_and_knife: 6 - Should style asserts based on [PyHamcrest](https://github.com/hamcrest/PyHamcrest).
* [:octocat: responses](https://github.com/dropbox/responses) - :star: 1336 :fork_and_knife: 122 - A utility library for mocking out the requests Python library.
* [:octocat: VCR.py](https://github.com/kevin1024/vcrpy) - :star: 754 :fork_and_knife: 116 - Record and replay HTTP interactions on your tests.
* [:octocat: FuckIt.py](https://github.com/ajalt/fuckitpy) - :star: 2140 :fork_and_knife: 89 - FuckIt.py uses state-of-the-art technology to make sure your Python code runs whether it has any right to or not.
* [:octocat: code2flow](https://github.com/scottrogowski/code2flow) - :star: 293 :fork_and_knife: 39 - Turn your Python and JavaScript code into DOT flowcharts.
* [:octocat: pycallgraph](https://github.com/gak/pycallgraph) - :star: 706 :fork_and_knife: 113 - A library that visualises the flow (call graph) of your Python application.
* [:octocat: pysonar2](https://github.com/yinwang0/pysonar2) - :star: 2282 :fork_and_knife: 622 - A type inferencer and indexer for Python.
* [:octocat: pyringe](https://github.com/google/pyringe) - :star: 1372 :fork_and_knife: 52 - Debugger capable of attaching to and injecting code into Python processes.
* [:octocat: django-debug-toolbar](https://github.com/django-debug-toolbar/django-debug-toolbar) - :star: 3853 :fork_and_knife: 701 - Display various debug information about the current request/response.
* [:octocat: django-devserver](https://github.com/dcramer/django-devserver) - :star: 1160 :fork_and_knife: 151 - A drop-in replacement for Django's runserver.
* [:octocat: flask-debugtoolbar](https://github.com/mgood/flask-debugtoolbar) - :star: 497 :fork_and_knife: 81 - A port of the django-debug-toolbar to flask.
* [:earth_americas: Biopython](http://biopython.org/wiki/Main_Page) - Biopython is a set of freely available tools for biological computation.
* [:earth_americas: blaze](http://blaze.pydata.org/en/latest/) - NumPy and Pandas interface to Big Data.
* [:earth_americas: cclib](http://cclib.github.io/) - A library for parsing and interpreting the results of computational chemistry packages.
* [:earth_americas: NetworkX](https://networkx.github.io/) - A high-productivity software for complex networks.
* [:earth_americas: Numba](http://numba.pydata.org/) - Python JIT (just in time) complier to LLVM aimed at scientific Python by the developers of Cython and NumPy.
* [:earth_americas: NumPy](http://www.numpy.org/) - A fundamental package for scientific computing with Python.
* [:earth_americas: Open Babel](http://openbabel.org/wiki/Main_Page) - A chemical toolbox designed to speak the many languages of chemical data.
* [:octocat: Open Mining](https://github.com/avelino/mining) - :star: 629 :fork_and_knife: 101 - Business Intelligence (BI) in Python (Pandas web interface)
* [:earth_americas: orange](http://orange.biolab.si/) - Data mining, data visualization, analysis and machine learning through visual programming or Python scripting.
* [:earth_americas: Pandas](http://pandas.pydata.org/) - A library providing high-performance, easy-to-use data structures and data analysis tools.
* [:earth_americas: PyDy](https://pydy.org/) - Short for Python Dynamics, used to assist with workflow in the modeling of dynamic motion based around NumPy, SciPy, IPython, and matplotlib.
* [:octocat: dpark](https://github.com/douban/dpark) - :star: 1943 :fork_and_knife: 445 - Python clone of Spark, a MapReduce alike framework in Python.
* [:octocat: dumbo](https://github.com/klbostee/dumbo) - :star: 980 :fork_and_knife: 160 - Python module that allows one to easily write and run Hadoop programs.
* [:octocat: luigi](https://github.com/spotify/luigi) - :star: 5573 :fork_and_knife: 1056 - A module that helps you build complex pipelines of batch jobs.
* [:octocat: mrjob](https://github.com/Yelp/mrjob) - :star: 1904 :fork_and_knife: 481 - Run MapReduce jobs on Hadoop or Amazon Web Services.
* [:octocat: CyToolz](https://github.com/pytoolz/cytoolz/) - :star: 297 :fork_and_knife: 26 - Cython implementation of Toolz: High performance functional utilities.
* [:octocat: fn.py](https://github.com/kachayev/fn.py) - :star: 2087 :fork_and_knife: 133 - Functional programming in Python: implementation of missing features to enjoy FP.
* [:octocat: funcy](https://github.com/Suor/funcy) - :star: 1342 :fork_and_knife: 66 - A fancy and practical functional tools.
* [:octocat: Toolz](https://github.com/pytoolz/toolz) - :star: 1227 :fork_and_knife: 102 - A collection of functional utilities for iterators, functions, and dictionaries.
*Libraries for accessing third party services APIs. See: [List of Python API Wrappers and Libraries](https://github.com/realpython/list-of-python-api-wrappers).*
* [:octocat: facepy](https://github.com/jgorset/facepy) - :star: 531 :fork_and_knife: 157 - Facepy makes it really easy to interact with Facebook's Graph API
* [:octocat: gmail](https://github.com/charlierguo/gmail) - :star: 1311 :fork_and_knife: 251 - A Pythonic interface for Gmail.
* [:octocat: google-api-python-client](https://github.com/google/google-api-python-client) - :star: 1199 :fork_and_knife: 551 - Google APIs Client Library for Python.
* [:octocat: honcho](https://github.com/nickstenning/honcho) - :star: 857 :fork_and_knife: 97 - A Python port of [Foreman](https://github.com/ddollar/foreman), a tool for managing Procfile-based applications.
* [:octocat: pexpect](https://github.com/pexpect/pexpect) - :star: 718 :fork_and_knife: 194 - Controlling interactive programs in a pseudo-terminal like GNU expect.
* [:earth_americas: APScheduler](http://apscheduler.readthedocs.org/) - A light but powerful in-process task scheduler that lets you schedule functions.
* [:earth_americas: TaskFlow](http://docs.openstack.org/developer/taskflow/) - A Python library that helps to make task execution easy, consistent and reliable.
* [:earth_americas: cffi](https://pypi.python.org/pypi/cffi) - Foreign Function Interface for Python calling C code.
* [:earth_americas: ctypes](https://docs.python.org/2/library/ctypes.html) - (Python standard library) Foreign Function Interface for Python calling C code.
* [:earth_americas: PyCUDA](http://mathema.tician.de/software/pycuda/) - A Python wrapper for Nvidia's CUDA API.
* [:earth_americas: SWIG](http://www.swig.org/Doc1.3/Python.html) - Simplified Wrapper and Interface Generator.
* [:earth_americas: Cython](http://cython.org/) - Optimizing Static Compiler for Python. Uses type mixins to compile Python into C or C++ modules resulting in large performance gains.
* [:earth_americas: PyPy](http://pypy.org/) - An implementation of Python in Python. The interpreter uses black magic to make Python very fast without having to add in additional type information.
* [:octocat: Pyston](https://github.com/dropbox/pyston) - :star: 4035 :fork_and_knife: 279 - A Python implementation built using LLVM and modern JIT techniques with the goal of achieving good performance.
* [:octocat: PythonNet](https://github.com/pythonnet/pythonnet) - :star: 252 :fork_and_knife: 83 - Python Integration with the .NET Common Language Runtime (CLR).
* [:earth_americas: Mininet](http://mininet.org/) - A popular network emulator and API written in Python.
* [:earth_americas: POX](http://www.noxrepo.org/pox/about-pox/) - An open source development platform for Python-based Software Defined Networking (SDN) control applications, such as OpenFlow SDN controllers.
* [:earth_americas: Pyretic](http://frenetic-lang.org/pyretic/) - A member of the Frenetic family of SDN programming languages that provides powerful abstractions over network switches or emulators.
* [:octocat: SDX Platform](https://github.com/sdn-ixp/internet2award) - :star: 9 :fork_and_knife: 5 - SDN based IXP implementation that leverages Mininet, POX and Pyretic.
* [:octocat: PyUserInput](https://github.com/SavinaRoja/PyUserInput) - :star: 464 :fork_and_knife: 117 - A module for cross-platform control of the mouse and keyboard.
* [:octocat: blinker](https://github.com/jek/blinker) - :star: 441 :fork_and_knife: 58 - A fast Python in-process signal/event dispatching system.
* [:octocat: itsdangerous](https://github.com/mitsuhiko/itsdangerous) - :star: 1014 :fork_and_knife: 86 - Various helpers to pass trusted data to untrusted environments.
* [:octocat: pluginbase](https://github.com/mitsuhiko/pluginbase) - :star: 428 :fork_and_knife: 44 - A simple but flexible plugin system for Python.
* [:octocat: Pychievements](https://github.com/PacketPerception/pychievements) - :star: 78 :fork_and_knife: 3 - A framework for creating and tracking achievements.
* [:octocat: SublimeJEDI](https://github.com/srusskih/SublimeJEDI) - :star: 669 :fork_and_knife: 72 - A Sublime Text plugin to the awesome auto-complete library Jedi.
* [:octocat: Anaconda](https://github.com/DamnWidget/anaconda) - :star: 1213 :fork_and_knife: 133 - Anaconda turns your Sublime Text 3 in a full featured Python development IDE.
* [:octocat: YouCompleteMe](https://github.com/Valloric/YouCompleteMe) - :star: 12073 :fork_and_knife: 1412 - Includes [Jedi](https://github.com/davidhalter/jedi)-based completion engine for Python.
* [:octocat: Jedi-vim](https://github.com/davidhalter/jedi-vim) - :star: 2535 :fork_and_knife: 217 - Vim bindings for the Jedi auto-completion library for Python.
* [:octocat: Python-mode](https://github.com/klen/python-mode) - :star: 3188 :fork_and_knife: 656 - An all in one plugin for turning Vim into a Python IDE.
* [:earth_americas: Travis CI](https://travis-ci.org) - A popular CI service for your open source and [private](https://travis-ci.com) projects. (GitHub only)
* [:earth_americas: CircleCI](https://circleci.com/) - A CI service that can run very fast parallel testing. (GitHub only)
* [:earth_americas: Vexor CI](https://vexor.io) - A continuous integration tool for private apps with pay-per-minute billing model.
* [:earth_americas: Wercker](http://wercker.com/) - A Docker-based platform for building and deploying applications and microservices.
